麻疹患儿并发急性呼吸窘迫综合征的危险因素

目的 探讨麻疹患儿并发急性呼吸窘迫综合征(ARDS)的危险因素。方法 回顾性分析PICU救治的55 例麻疹患儿的临床资料,其中11 例并发ARDS。采用单因素分析和非条件logistic 多因素回归分析筛选ARDS 发病的危险因素。结果 单因素分析显示,ARDS 组和非ARDS 组患儿入院时吸氧方式(鼻导管/面罩)、合并脓毒症比例、血C 反应蛋白(CRP)水平及淋巴细胞计数差异有统计学意义(P<0.05)。多因素logistic回归分析显示合并脓毒症和血CRP 水平增高是麻疹并发ARDS 的主要危险因素(OR 分别为116.444、1.050,P<0.05)。结论 合并脓毒症及血CRP 水平增高的麻疹患儿并发ARDS 的风险增加。

Risk factors for the development of acute respiratory distress syndrome in children with measles

Objective To study the risk factors for the development of acute respiratory distress syndrome (ARDS) in children with measles. Methods The clinical data of 55 children with measles were retrospectively studied. Of the 55 children, 11 were complicated by ARDS. The risk factors for the development of ARDS were investigated by univariate analysis and multivariate non-conditional logistic regression analysis. Results The univariate analysis showed that there were significant differences in the oxygen inhalation mode (nasal catheter/mask), the rate of sepsis, blood C-reactive protein (CRP) levels and lymphocyte counts at admission between the ARDS and non-ARDS groups (P<0.05). The presence of sepsis and higher blood CRP levels were identified as the major risk factors for the development of ARDS by the multivariate logistic regression analysis (OR=116.444, 1.050 respectively; P<0.05). Conclusions The children with measles who have sepsis and higher blood CRP levels are at risk of ARDS.