Microbial transformation of azacarbazoles. VIII. Production of 14C-labelled benzo-alpha-iso-carbolines by permeabilized cells of Kitasatosporia setae strain |
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| Authors: | W Peczyńska-Czoch |
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| Affiliation: | Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroc?aw. |
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| Abstract: | ![]()
N-1 methylation of benzo-alpha-carbolines performed with Kitasatosporia setae strain yields corresponding benzo-alpha-iso-carbolines, compounds demonstrating relatively strong cytostatic and antitumor properties. To obtain radioactive benzo-alpha-iso-carbolines required for the further studies of their mode of antitumor action, a simple and useful method of the preparation of 14C-labelled compounds by microbial means has been elaborated. |
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