何首乌炮制后化学成分及药理作用的研究进展

何首乌作为我国传统中医常用的滋补药,在临床上应用很广泛,尤其是补肝方面,但是最近几年临床上一直有关于何首乌生品及炮制品引起肝损伤的不良反应产生,引起了研究人员的关注。本文就其总结了近年来关于何首乌生品及炮制品的相关报道,从何首乌的炮制历史沿革、炮制工艺、炮制对药物化学成分变化和药理作用的影响等方面进行了总结和归纳。何首乌生品及炮制品的化学成分、药理作用方面均存在一定的差异,考虑到临床用药的安全性、有效性及中成药的质量稳定性,在使用过程中应区分使用并注意合理用药,为正确应用何首乌提供参考依据。

Progress in Study on Chemical Constituents and Pharmacological Action of Polygoni Multiflori Radix After Being Processed

As a common tonic medicine in traditional Chinese medicine,especially on liver,but in recent years,there have been liver injury report in clinical caused by raw products and processed products of Polygoni Multiflori Radix,so this herb attracted the attention of researchers.This paper summarizes the relevant reports on raw products and processed products of Polygoni Multiflori Radix in recent ten years,including processing history,processing technology,effects of processing on the change of chemical constituents and pharmacological action.Chemical constituents and pharmacological action of raw products and processed products are different,taking into account the safety and effectiveness of clinical medication and the quality stability of Chinese patent medicine,in the course of using,we should be distinguished from application and pay attention to the rational use of drugs.This paper can provide scientific basis for the correct application of Polygoni Multiflori Radix.