细胞减瘤术联合腹腔热灌注化疗治疗在结直肠癌腹膜转移的临床应用

结直肠癌腹膜转移是结直肠癌的终末期病变，预后较差，多采用保守治疗。近年来，细胞减瘤术联合腹腔热灌注化疗治疗结直肠癌腹膜转移逐渐被接受，可显著改善患者的预后，但由于其设备的缺乏、手术的复杂、并发症相对较多等原因未得到普遍应用。本文对其理论基础、技术方法、临床研究及风险与安全等方面进行了综述，探索结直肠癌腹膜转移的多模式治疗方案，进一步提高结直肠癌腹膜转移患者的治疗效果。

Clinical Application of Cytoreductive Surgery Combined with Intraperitoneal Hyperthermic Perfusion Chemotherapy in Peritoneal Metastasis of Colorectal Cancer

Peritoneal metastasis of colorectal cancer is an end-stage disease of colorectal cancer with poor prognosis, and conservative treatment is often used. In recent years, cell cytoreductive surgery combined with intraperitoneal hyperthermic perfusion chemotherapy for the treatment of colorectal cancer peritoneal metastasis is gradually accepted, can significantly improve the prognosis of patients, but due to lack of equipment, complicated surgery, relatively more complications, etc. application. This article reviews its theoretical basis, technical methods, clinical research and risk and safety, explores multi-modal treatment of colorectal cancer peritoneal metastasis, and further improves the therapeutic effect of patients with colorectal cancer peritoneal metastasis.