血糖及糖化血红蛋白的检测及干扰研究进展

2010年美国糖尿病协会将糖化血红蛋白（HbA1c）检测作为筛选和诊断糖尿病指标，其参考界值为HbA1c≥6.5%。至此，HbA1c同血糖一样正式成为糖尿病诊断检测指标。血糖及HbA1c作为杰出的糖尿病诊疗指标，其检验方法灵活多变且较易受外界多种因素影响，干扰检测结果的准确性。随着检验技术的进步，临床与糖尿病诊疗相关的生物传感器的应用逐渐广泛，本文将针对二者常见检测方法的干扰因素做一综述。

Progress in Detection and Interference of Blood Glucose and Glycated Hemoglobin

In 2010, the American Diabetes Association used glycosylated hemoglobin (HbA1c) as a screening and diagnostic diabetes indicator with a reference margin of HbA1c ≥ 6.5%. At this point, HbA1c has officially become a diagnostic indicator for diabetes, just like blood sugar. Blood glucose and HbA1c are excellent indicators for diagnosis and treatment of diabetes. The test methods are flexible and changeable, and are more susceptible to various external factors, which interferes with the accuracy of test results. With the advancement of testing technology, the application of biosensors related to clinical diagnosis and treatment of diabetes has become more and more extensive. This paper will review the interference factors of common detection methods.