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| 脂蛋白相关磷脂酶A2与冠心病的研究 | |
| 引用本文： | 薛 一1,孔莫维1,高 宇2. 脂蛋白相关磷脂酶A2与冠心病的研究[J]. 医学信息, 2019, 0(12): 53-56. DOI: 10.3969/j.issn.1006-1959.2019.12.017 |
| 作者姓名： | 薛 一1 孔莫维1 高 宇2 |
| 作者单位： | 1.承德医学院，河北 承德 067000；2.承德医学院附属医院内分泌科，河北 承德 067000 |
| 摘 要： | 在过去的几十年中，炎症在动脉粥样硬化发病机制中的作用一直是研究的热点。研究表明一些炎症标志物对冠心病（CHD）的首发和已确诊CHD患者疾病复发具有预测价值。在这些标记中，脂蛋白相关磷脂酶A2（Lp-PLA2）最近受到了相当的关注。本文对Lp-PLA2作为CHD风险标志物和作为治疗靶点的潜在作用进行综述。 |
| 关 键 词： | 脂蛋白相关磷脂酶A2 冠心病 动脉粥样硬化 |
Research on Lipoprotein-associated Phospholipase A2 and Coronary Heart Disease |
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| XUE Yi1,KONG Mo-wei1,GAO Yu2. Research on Lipoprotein-associated Phospholipase A2 and Coronary Heart Disease[J]. Medical Information, 2019, 0(12): 53-56. DOI: 10.3969/j.issn.1006-1959.2019.12.017 | |
| Authors: | XUE Yi1 KONG Mo-wei1 GAO Yu2 |
| Affiliation: | 1.Chengde Medical College,Chengde 067000,Hebei,China;2.Department of Endocrinology,Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China |
| Abstract: | Abstract:In the past few decades, the role of inflammation in the pathogenesis of atherosclerosis has been a hot topic of research. Studies have shown that some inflammatory markers have predictive value for the onset of coronary heart disease (CHD) and the recurrence of disease in patients with confirmed CHD. Among these markers, lipoprotein-associated phospholipase A2 (Lp-PLA2) has recently received considerable attention. This review summarizes the potential role of Lp-PLA2 as a CHD risk marker and as a therapeutic target. |
| Keywords: | Key words:Lipoprotein-associated phospholipase A2 Coronary heart disease Atherosclerosis |
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