脊柱结核患者血常规参数的变化及其临床意义

目的 研究脊柱结核患者血常规中各项参数的变化及其临床意义。方法 选取宁夏医科大学总医院2017年1月~2018年6月收治的脊柱结核患者70例为研究组，对照组为同期该院体检中心体检的健康人员70例。统计两组血常规中的参数值，比较两组之间的差异。结果 与对照组相比，研究组的白细胞总数（WBC）无明显变化（P＞0.05），中性粒细胞计数（NEU）、单核细胞计数（MXD）增加，淋巴细胞计数（LYM）减少，单核细胞/淋巴细胞比例（M/L）增加（P＜0.05）；研究组存在轻度贫血，表现为红细胞计数（RBC）、血红蛋白含量（HGB）、平均红细胞HGB含量（MCH）、平均红细胞HGB浓度（MCHC）、红细胞压积（HCT）下降，红细胞分布宽度（RDW）增加（P＜0.05）；研究组的血小板计数（PLT）和血小板压积（PCT）明显增加（P＜0.05）。结论 与健康体检人员相比，脊柱结核患者的血常规中某些参数值存在异常，可能为脊柱结核的早期诊断提供依据。

Changes of Blood Routine Parameters in Patients with Spinal Tuberculosis and Its Clinical Significance

Abstract:Objective To study the changes of various parameters in blood routine of patients with spinal tuberculosis and its clinical significance. Methods 70 patients with spinal tuberculosis admitted to the General Hospital of Ningxia Medical University from January 2017 to June 2018 were selected as the study group. The control group was 70 healthy subjects in the physical examination center of the hospital. The parameter values in the blood routine of the two groups were counted, and the difference between the two groups was compared.Results Compared with the control group, the total white blood cell count (WBC) of the study group did not change significantly (P>0.05), the neutrophil count (NEU), the monocyte count (MXD) increased, and the lymphocyte count (LYM) decreased. Monocyte/lymphocyte ratio (M/L) increased (P<0.05); the study group had mild anemia, showing red blood cell count (RBC), hemoglobin content (HGB), mean red blood cell HGB content (MCH), mean red blood cells HGB concentration (MCHC), hematocrit (HCT) decreased, and red blood cell distribution width (RDW) increased (P<0.05). The platelet count (PLT) and platelet pressure (PCT) of the study group increased significantly (P<0.05).Conclusion Compared with healthy medical examines, some parameters of blood routine in patients with spinal tuberculosis are abnormal, which may provide a basis for early diagnosis of spinal tuberculosis.