胃肠息肉患者血脂水平影响因素及相关性分析

目的 分析胃肠息肉与血脂水平的相关性。方法 选取2016年8月~2017年12月合肥市第一人民医院消化内科住院的胃息肉患者114例和肠息肉患者135例作为病例组，体检健康中心非息肉患者110例为对照组。收集三组患者空腹TG、TC、LDL-C、HDL-C水平，同时收集息肉患者的息肉病理类型、大小、数量、部位等临床特点，采用回归分析对各组血脂情况进行分析。另外收集胃息肉患者是否患有Hp感染、慢性胃炎，肠息肉患者是否患有高血压、高血糖、高尿酸、脂肪肝，分析各因素对血脂水平影响。结果 ①胃息肉组的血清TG、

Influential Factors and Correlation Analysis of Blood Lipid Levels in Patients with Gastrointestinal Polyps

Objective To analyze the correlation between gastrointestinal polyps and blood lipid levels. Methods A total of 114 patients with gastric polyps and 135 patients with intestinal polyps were enrolled in the Department of Gastroenterology, First People's Hospital of Hefei from August 2016 to December 2017. A total of 110 patients with non-polyposis in the physical examination health center were selected as the control group. The levels of fasting TG, TC, LDL-C and HDL-C were collected from three groups. The clinical characteristics of polyp pathology, size, quantity and location of polyps were collected. The blood lipids of each group were analyzed by regression analysis. In addition, patients with gastric polyps were diagnosed with Hp infection, chronic gastritis, whether patients with intestinal polyps had hypertension, hyperglycemia, high uric acid, and fatty liver. The effects of various factors on blood lipid levels were analyzed. Results ①The serum TG and TC of the gastric polyp group were higher than the control group, and the HDL-C was lower than the control group,the difference was statistically significant (P<0.05). Serum TG in patients with Hp-infected gastric polyps was higher than in patients without HP infection. There were no significant differences in blood lipid levels between different pathological types, sizes, and quantitative sites of gastric polyps (P>0.05).②Serum TG and TC were higher in the intestinal polyp group than in the control group, and HDL-C was lower than the control group, the difference was statistically significant (P<0.05). There were significant differences in blood lipid levels between the polyp>1 cm group and the <1 cm group, the left colon polyps group and the right colon colon polyp group,the difference was statistically significant (P<0.05). There was no significant difference in serum lipid levels between the adenomatous polyp group and the non-adenomatous group, single-shot group and multiple-shot group (P>0.05). There was a significant correlation between high uric acid and fatty liver in patients with intestinal polyps and hyperlipidemia (P<0.05). Conclusion The blood lipid level of patients with gastrointestinal polyps is abnormal. The dyslipidemia of patients with gastric polyps is related to Hp infection. It is recommended to eradicate Hp in patients with gastric polyps, reduce dyslipidemia, and prevent other diseases. Hyperlipidemia in patients with intestinal polyps is a risk factor for the progression of polyps, and patients with intestinal polyps with high uric acid and fatty liver are at greater risk for hyperlipidemia.