双氯芬酸钠栓致过敏反应

1例65岁男性患者,因肾绞痛使用双氯芬酸钠栓(50 mg),10 min后出现颜面及全身皮肤发红、胸闷、呼吸急促,心率增快、烦躁不安.立即给予吸氧(3 L/min),静脉滴注10％葡萄糖500 ml,地塞米松10 mg入莫菲滴管和皮下注射盐酸肾上腺素1.0 mg,症状好转.70 min后患者再次出现烦躁不安、呼吸急促、...

Anaphylactic reactions due to diclofenac suppository

A 65-years-old man with renal colic received a suppository of diclofenac 50 mg.Ten minutes later,the patient developed facial and generalized flushing,chest tightness,short of breath,tachycardia and dysphoria.Oxygen inhalation 3 L/min,an IV infusion of 10% glucose 500 ml,dexamethasone 10 mg via a Murphy＇ s dropper,and SC adrenaline hydrochloride 1.0 mg were given immediately,and then his symptoms subsided.Seventy minutes later,the patient developed dysphoria,short of breath,and tachycardia again.SC adrenaline hydrochloride 0.5 mg was readministered.Twenty minutes later,the patient gradually became quiet with normal respiration.Ten hours after receiving the diclofenac suppository,facial and generalized flushing disappeared.