鬏杏达莫对原发性肾病综合征患者血液流变学的影响及其疗效分析

目的探讨银杏达莫治疗原发性肾病综合征（PNS）的临床疗效及其对血液流变学的影响。方法将我院收治的92例PNS患者随机分为治疗组和对照组，每组各46例。两组均给予常规对症治疗，治疗组采用银杏达莫注射液治疗，对照组采用丹参注射液治疗，疗程为4周。观察两组治疗前后24h尿蛋白定量、血清白蛋白、血液流变学指标的变化。结果治疗组总有效率为82．6％，显著优于对照组的63．O％，差异有统计学意义（P〈0．05）；两组治疗后血液流变学指标较治疗前均有所改善，而治疗组的改善程度显著优于对照组（P〈0．05）；两组未见不良反应。结论银杏达莫注射液治疗PNS安全、有效，具有明显改善患者血液高凝状态的作用。

Influence and effect of Gingko Damo on blood rheology of patients with primarily hydremic nephritis

Objective To explore the influence of injection Gingko damo on blood rheology and its clinical effect in patients with primarily hydremic nephritis(PNS).Methods 92 PNS patients who were treated in our hospital were divided into two groups.Both groups were given symptomatic treatment regularly.The treatment group and control group was treated with injection Gingko damo and Danshen injection for 4 weeks,respectively.The changes of 24-hours urine protein fixed quantity,serum albumin and rheology were compared between the two groups before and after treatment.Results The effective rate in the treatment group and control group was 82.6% and 63.0%,the difference was statistically significant(P < 0.05).The indicators of blood rheology were significantly improved in both groups after treatment,while the treatment group improved more remarkably compared with the control group(P < 0.05).No obvious adverse reaction was found in both groups.Conclusion It is safe and effective for injection Gingko damo in treatment of PNS,and it can contribute to obviously improve blood hypercoagulabale state.