三维适形放疗联合化疗及中药治疗中晚期食管癌疗效观察

目的 观察三维适形放疗联合化疗及中药治疗中晚期食管癌的临床疗效.方法 36例中晚期食管癌患者,随机分为两组,对照组给予常规放、化疗,治疗组应用三维适形放疗联合化疗及中药治疗,比较两组患者的近期疗效、毒性反应及远期疗效,并对患者死亡原因进行分析.结果 治疗组完全缓解率明显高于对照组(P＜0.05);毒性反应减低;两组患者1、3年生存率有显著性差异(P＜0.05),5年生存率无显著性差异(P＞0.05);局部未控制及复发率明显低于对照组(P＜0.05).结论 采用三维适形放疗联合化疗及中药对中晚期食管癌的治疗效果优于常规放、化疗法.

Observation on Treatment of Advanced Esophageal Carcinoma with Three-Dimensional Conformal Radiotherapy Combined with Chemotherapy and Traditional Chinese Medicine

Objective To observe the clinical effect of treating advanced esophageal carcinoma with three-dimensional conformal radiotherapy combined with chemotherapy and traditional Chinese medicine.Methods 36 cases with advanced esophageal carcinoma were randomly divided into a eontrol group and a treatment group.The control group was treated with conventional radiotherapy combined with chemotherapy,and the treatment group was treated with three-dimensional conforrnal radiotherapy combined with chemotherapy and traditional Chinese medicine.The short-term effect,toxicity and long-term effect were observed,and cause of death was analyzed.Results The complete remission rate in the treatment group was significantly higher than that of the control group(P＜0.05).The toxicity of the treatment group was markedly decreased.One and three years'survival rate between the two groups had a significant difierent(P＜0.05),but five years'survival rate between the two groups had no significant difference(P＞0.05).Local uncontrolled rate and recurrence rate in the treatment group were significantly lower than those in the control group(p＜0.05).Conclusion The treatment of three-dimensional conformal radiotherapy combined with chemotherapy and traditional Chinese medicine on advanced esophageal carcinoma was better than conventional radiotherapy combined with chemotherapy.