喉癌发病及影响生存率的因素分析（附98例报告）

本组通过对９８例喉癌临床资料分析提示喉癌的发病与性别、年龄、吸烟嗜好有明显关系，男女发病之比为６：１．高峰年龄段在５１岁—６０岁，儿童及青少年极罕见．８６．７％的患者有吸烟嗜好，且吸烟史均在１０年—３０年以上．喉癌的颈淋巴结转移与病期和肿瘤部位有明显关系，主要发生在声门上型和Ｔ３Ｔ４期．局部复发及颈淋巴结转移是喉癌死亡的主要原因，远处转移较少见．影响喉癌生存率的主要因素是发病部位和病灶范围，声门癌３年、５年生存率分别为声门上癌的１．８倍和２．４倍；Ｔ１Ｔ２期３年、５年生存率分别为Ｔ３Ｔ４的２．９倍和５．４倍．

An Analysis of Pathogenesis and Factors Affectiug Survival Rate of Laryngocarcinoma-Repor of 98 Cases

Abstract The analysis of clinical datum of 98 patients revealed that morbility of laryngocarcinoma obviously related to sex, age and liking for smoking. The results showed that the ratio of male to female was 6 to 1, peak age-segment was 51-60 years old, and this carcinoma was rarely seen in children or youth and youthsters 86. 7 % of them had a liking for smoking in a history over 10-30 years. The cervical lymphoatic metastasis of laryngocarcinoma, which mainly occurred in supraglottic type and T3 T4 stage related to duration of illness and region of tumor. Local recurrencey and cervical lymphatic metas tas is were major cause of death butdi s taut metastas is was rare.The analysis indicates that the main factors affecting survival rate are pathogenic region and s lie of primary focus. The 3 or 5 year survival rate for glottic group was 1. 8 times and 2. 4 times of that of supraglottic group, and that for T1 T2 group were 2. 9 times and 5. 4 times of that of T3 T4 group.