肺出血-肾炎综合征1例报告并文献复习

目的 :探讨肺出血 -肾炎综合征的临床特点。方法 :结合病例复习文献。结果 :该病的发生与流感病毒、接触汽油、松节油甚至吸烟、混凝土粉尘有关。发病机理与肺泡基底膜、肾小球基底膜共同形成抗原抗体复合物有关。发病以青年男性多见 ,临床特征为咯血、贫血、尿检异常及肾功进行性减退。胸片异常者只有 2 0 %左右。治疗包括血浆置换、激素、免疫抑制剂的应用等。结论 :对该病应加强认识 ,早期诊断、早期治疗 ,才能提高生存率。

Goodpasture Syndrome: A Case Report and Literature Review

Objective:To explore the clinical characteristics of Goodpasture syndrome.Methods:Case report combined with literature review.Results:The occurrence of this disease is related to flu-viruses infection, contacts of gasoline,turpentine, and concrete dust,and smoking. The pathological changes were characterized by formation of antigen-antibody complexes both in the alveoli basement-membrane and the glomerular basement-membrane.Most of patients were young males. The clinical characteristies were haemoptysis, anemia, abnormal urine and progressive decline of renal function. About 20% patients presented abnormal chest x-ray manifestation. Clinical therapy included plasma exchange, hormone treatment and use of immune inhibitors.Conclusion:It is important to reinforce the knowledge of this disease. Early diagnosisand early therapy may improve the survival rate. by early diagnosis ang treatment.