75例儿童重症药疹临床分析

目的：分析我院儿童重症药疹的临床特点。方法：对我院75例儿童重症药疹患者临床资料进行回顾性分析。结果：75例患儿发病年龄0~17岁，其中婴儿期13例（17.33%），1~3岁11例（14.67%），3~6岁13例（17.33%），6~12岁33例（44.00%），12~18岁5例（6.67%）；SJS 44例（58.60%），DHS 20例（26.60%），TEN 11例（14.60%）。常见致敏药物为抗生素类（33例，44.00%），解热镇痛类（14例，18.67%），抗癫痫类（13例，17.33%）。结论：我院儿童重症药疹主要致敏药物为抗生素类，好发年龄为6~12岁，最常见的类型为SJS。

Clinic analysis of 75 chiliren with severe drug eruption

Objective: To analyze clinic characteristic of children with severe drug eruption in our hospital. Methods: The data of 75 children with severe drug eruption in our hospital were analyzed retrospectively. Results: The age of onset of 75 patients was from 3 months to 17 years. Of 75 patients, 13 (17.33%) were younger than 1 year old, 11 (14.67%) aged from 1 to 3 years, 13 (17.33%) aged from 3 to 6 years, 33 (44.00%) aged from 6 to 12 year, 5 (6.67%) aged from 12 to 18 year. The type of severe drug eruption included SJS in 44 patients (58.6%), DHS in 20 patients (26.6%), TEN in 11 patients (14.6%). The common sensitizing drugs were antibiotics in 33 patients (44.00%), antipyretic and analgesic drugs in 14 patients (18.67%), antiepileptic drugs in 13 patients (17.33%). Conclusion: Antibiotics is the most sensitizing drugs for severe drug eruption in children, the peak age is from 6 to 12 years, and the most common tyoe was SJS.