显微喉镜下CO2激光治疗累及前连合T1期声门区高分化鳞状细胞癌

目的〓〖HTK〗探讨显微喉镜下应用CO2激光治疗累及前连合T1期声门区高分化鳞状细胞癌的效果。〖HTW〗方法〓〖HTK〗回顾性分析56例T1期声门区高分化鳞状细胞癌于显微喉镜下施行CO2激光切除术的临床资料。〖HTW〗结果〓〖HTK〗11例（19.6％）局部复发,其中4例（4/37）为单侧病变,5例（5/13）为单侧声带与前连合病变,2例（2/6）为“马蹄样”病变。3组不同病变组术后复发率差异有统计学意义（P＜0.05）,且单侧声带累及前连合组与“马蹄样”病变组的复发率均高于单侧声带病变组。56例随访平均26个月（10～32个月）,喉功能保留率96.4％。〖HTW〗结论〓〖HTK〗显微喉镜下激光治疗前连合癌具有一定的局限性,对于累及前连合T1期声门癌应慎重施行显微喉镜下激光切除。

CO2 laser in treatment of T1 well-differentiated squamouscell carcinoma in the glottic portion involving the anterior commissure under microscopy

Objective〓〖WTBZ〗To evaluate the oncologic safety of microscopic CO2 laser in treatment of stage T1 well-differentiated squamous cell carcinoma in the glottic portion involving the anterior commissure. 〖WTHZ〗Method〓〖WTBZ〗The clinical data of 56 cases from March 2005 to June 2007 were retrospectively analyzed. 〖WTHZ〗Results〓〖WTBZ〗11 cases (19.6%) locally recurred, of them, 4 cases (4/37) were unilateral cord lesion, 5 (5/13) were cord and anterior commissure lesion, and 2 (2/6) were horseshoes lesion involving both the cords and the anterior commissure. The recurrent rate of cases of cord and anterior commissure lesion and horseshoes lesion was higher than that of unilateral cord lesion. Followed up for an average of 26.4 months (10-32 months), the preservation rate of the laryngeal function was 96.4%. 〖WTHZ〗Conclusion〓〖WTBZ〗Microscopic CO2 laser for glottic carcinoma is limited to some extent, and it should be carefully used in carcinoma involving the anterior commissure.