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A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq |
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| Authors: | Angela C. Boroughs Rebecca C. Larson Nemanja D. Marjanovic Kirk Gosik Ana P. Castano Caroline B.M. Porter Selena J. Lorrey Orr Ashenberg Livnat Jerby Matan Hofree Gabriela Smith-Rosario Robert Morris Joshua Gould Lauren S. Riley Trisha R. Berger Samantha J. Riesenfeld Orit Rozenblatt-Rosen Bryan D. Choi Aviv Regev Marcela V. Maus |
| Affiliation: | 1. Cellular Immunotherapy Program and Cancer Center, Massachusetts General Hospital, Charlestown, MA 02129, USA;2. Harvard Medical School, Boston, MA 02115, USA;3. Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA;4. Howard Hughes Medical Institute, Koch Institute of Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02140, USA;5. Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA |
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