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| 缺氧缺血性脑损伤与凋亡的进展 | |
| 引用本文： | 陈敏榕,陈燕惠. 缺氧缺血性脑损伤与凋亡的进展[J]. 中国病理生理杂志, 2004, 20(7): 1318-1321 |
| 作者姓名： | 陈敏榕 陈燕惠 |
| 作者单位： | 1.福建医科大学附属协和医院儿科,福建,福州,350001 |
| 摘 要： | Apoptosis is one of the most important causes, which results in the central neuronal system complication in hypoxic- ischemic brain damage (HIBD). Apoptosis occurs in the developing brain more than in the developed brain. Apoptosis can last several weeks and may be inverted its pathology by appropriate therapy. Caspase inhibitor, neurotrophic factors, anti-apoptosis gene Bcl-2, mild hypothermia, and early intervention play important roles in promoting neuronal cell survival and preventing from apoptosis through different mechanisms. It may be a new way for rehabilitation of HIBD. |
| 关 键 词： | 细胞凋亡 缺氧缺血 脑 |
| 文章编号： | 1000-4718(2004)07-1318-04 |
| 收稿时间： | 2002-12-17 |
| 修稿时间： | 2003-03-31 |
Research progress in apoptosis and hypoxic - ischemic brain damage |
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| CHEN Min-rong,CHEN Yan-hui. Research progress in apoptosis and hypoxic - ischemic brain damage[J]. Chinese Journal of Pathophysiology, 2004, 20(7): 1318-1321 | |
| Authors: | CHEN Min-rong CHEN Yan-hui |
| Affiliation: | 1.Department of Pediatric, Union Hospital, Fujian Medical University,Fuzhou,China,350001 |
| Abstract: | Apoptosis is one of the most important causes, which results in the central neuronal system complication in hypoxic-ischemic brain damage (HIBD). Apoptosis occurs in the developing brain more than in the developed brain. Apoptosis can last several weeks and may be inverted its pathology by appropriate therapy. Caspase inhibitor, neurotrophic factors, anti-apoptosis gene Bcl-2, mild hypothermia,and early intervention play important roles in promoting neuronal cell survival and preventing from apoptosis through different mechanisms. It may be a new way for rehabilitation of HIBD. [ |
| Keywords: | Apoptosis Hypoxia-ischemia brain |
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