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Cytotoxicity of urushiols isolated from sap of Korean lacquer tree (Rhus vernicifera stokes)
Authors:Dong Ho Hong  Sang Bae Han  Chang Woo Lee  Se Hyung Park  Young Jin Jeon  Myong-Jo Kim  Sang-Soo Kwak  Hwan Mook Kim
Affiliation:Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon.
Abstract:
Cytotoxicities of four urushiols, congeners isolated from the sap of Korean lacquer tree (Rhus vernicifera Stokes), to 29 human cancer cell lines originated from 9 organs were evaluated. Their values of 50% growth inhibition were below 4 microg/ml, and showed cell line specific cytotoxicity. The present result is the first report on the cytotoxicity of urushiols suggesting that they would have an anticancer activity to human cancer cells.
Keywords:Urushiols  Cytotoxicity  Human Cancer Cells
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