超敏C反应蛋白与碱性磷酸酶联合检测对骨伤患者术后感染的临床意义

目的探讨超敏C反应蛋白与碱性磷酸酶在发生手术后感染的骨病患者中的改变及治疗意义。方法选取89例发生手术后感染的骨病患者为实验组,85例没有发生感染的骨病患者作为对照组,测定手术前后血清超敏C反应蛋白与碱性磷酸酶的浓度,并进行比较研究。结果实验组超敏C反应蛋白为(6.9±3.2)mg/L,对照组超敏C反应蛋白为(3.7±1.3)mg/L,两组统计学差异显著(P<0.05);实验组碱性磷酸酶为(162±21.5)u/L,对照组为(141±29.8)u/L,两组统计学差异显著(P<0.05)。结论超敏C反应蛋白与碱性磷酸酶联合测定对手术后合并感染的骨病患者具有重要的诊断及疗效评价意义。

The Clinical Significance of High-sensitivity C-reactive Protein and Alkaline Phosphatase in the Diagnosis of Postoperative Infection in Patients with Bone Injury

Objective To explore the changes and clinical significance of high-sensitivity C-reactive protein (hs-CRP) and alkaline phosphatase (ALP) in patients of bone injury with postoperative infection. Methods Eighty-nine patients of bone injury with postoperative infection were selected as experimental group and 85 patients without postoperative infection were selected as control group. The concentration of hs-CRP and ALP before and after operation were detected and compared. Results The hs-CRP concentration in experimental group and control group were (6.9 ± 3.2) mg/L and (3.7±1.3) mg/L respectively, and the difference had statistical significance (P <0.05). The ALP concentration in experimental group and control group were (162 ± 21.5) u/L and (141 ± 29.8) u/L respectively, and the difference had statistical significance (P <0.05). Conclusions The combined detection of high-sensitivity C-reactive protein and alkaline phosphatase in patients of bone injury with postoperative infection has improtant significance of diagnosis and therapeutic evaluation.