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| 纳米磁性对比剂在体内巨噬细胞相关疾病MRI成像中的应用 | |
| 引用本文： | 董银梅,陈怀文,刘崎. 纳米磁性对比剂在体内巨噬细胞相关疾病MRI成像中的应用[J]. 第二军医大学学报, 2015, 36(5): 536-541 |
| 作者姓名： | 董银梅 陈怀文 刘崎 |
| 作者单位： | 第二军医大学长海医院影像医学科,上海,200433 |
| 基金项目： | ] 国家自然科学(81270413). National natural science foundation project (81270413). |
| 摘 要： | 纳米磁性对比剂已成为MRI对比剂研究的重要方向,其独特的理化性质及生物学特性展示出良好的应用前景,并在临床诊断及科研工作中发挥着日益重要的作用.纳米磁性对比剂具有特殊的理化及生物学特性,容易被体内组织中巨噬细胞所吞噬,进而引起相关病灶部位MRI信号强度的变化,利于进行疾病的定量分析,具有广阔的应用前景.因此,本文就纳米磁性对比剂在巨噬细胞相关疾病MRI成像中的应用研究进行综述. |
| 关 键 词： | 磁性纳米材料 巨噬细胞 对比剂 磁共振成像 |
| 收稿时间： | 2014-12-30 |
| 修稿时间： | 2015-03-04 |
Current research on application of nano-magnetic contrast agent in MR imaging for macrophage in human diseases |
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| DONG Yin-mei,CHEN Huai-wen and LIU Qi. Current research on application of nano-magnetic contrast agent in MR imaging for macrophage in human diseases[J]. Former Academic Journal of Second Military Medical University, 2015, 36(5): 536-541 | |
| Authors: | DONG Yin-mei CHEN Huai-wen LIU Qi |
| Affiliation: | Department of Radiology,Changhai Hospital,Second Military Medical University,Department of Radiology,Changhai Hospital,Second Military Medical University,Department of Radiology,Changhai Hospital,Second Military Medical University |
| Abstract: | Nano-magnetic contrast agent has become one of the important research directions of MRI contrast agent, its unique physical and chemical properties and biological characteristics presented a good prospect of application and played an increasingly important role in clinical and research work. This review discusses the recent progress on nano-magnetic contrast agent and their applications for imaging macrophages in human diseases. |
| Keywords: | magnetic nanomaterials macrophages USPIO contrast agent magnetic resonance imaging |
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