银杏达莫注射液联合西药治疗慢性阻塞性肺病加重期疗效观察及其对血栓前状态指标的影响

目的分析银杏达莫注射液联合西药治疗慢性阻塞性肺病(COPD)加重期疗效观察及其对血栓前状态指标的影响。方法选取自2014年1月至2015年5月期间,我院的90例COPD加重期的患者进行研究分析。随机分为对照组和观察组各45例。对照组单独采用西药进行治疗,观察组采用银杏达莫注射液联合西药进行治疗。对比两组患者治疗前后的血栓前状态参数指标及血液流变学变化,治疗后的治疗疗效、不良反应情况及患者对疗效的满意度。结果对照组患者的总有效率为77.78%,明显低于观察组患者的95.56%(P0.05)。两组患者的血栓前状态参数与治疗前相比均有改善(P0.05);且对照组患者的改善情况明显低于观察组的患者(P0.05)。两组患者治疗后的红细胞比容、全血黏度、全血还原黏度、血浆黏度较治疗前相比改善情况均较为显著(P0.05),且对照组患者改善情况明显低于观察组(P0.05)。结论银杏达莫注射液联合西药对COPD加重期患者进行治疗疗效显著,且能改善患者的血栓前状态参数指标及血液流变学变化。。

Ginkgo Biloba Da Mo Injection Combined Western Medicine in the Treatment of Chronic Obstructive Pulmonary Disease;Aggravating Period Curative Effect Observation and Their Status Indicators on Thrombosis

Objective To analyze ginkgo da mo injection combined western medicine in the treatment of chronic obstructive pulmonary disease (COPD)aggravating period curative effect observation and their status indicators on thrombosis.Methods From January 2014-May 2015,our hospital 90 cases of patients with COPD aggravating period for study.All patients with random method can be divided into control group and observation group all 45 cases.The control group with western medicine alone treatment,observation group used in ginkgo biloba injection combined western medicine treatment.Compared two groups of patients before and after treatment of thrombosis state parameters and changes of hemorheology before treatment after treatment efficacy,adverse reactions of curative effect and patients satisfaction.Results Control group total effective rate of the patients was 77.78％ were markedly improved significantly less than 95.56％ of the observation group of patients,(P ＜ 0.05).Before the two groups of patients with thrombus state parameter compared with before treatment were improved significantly (P ＜ 0.05);And the control group on the improvement of their patients significantly lower than the observation group of patients with significant difference(P ＜ 0.05).Two groups of patients after treatment of RBC hematocrit,whole blood viscosity,whole blood reductive viscosity,blood plasma viscosity was compared to improve the situation were more significant (P ＜ 0.05),improve patients significantly lower than the observation group and control group (P ＜ 0.05).Conclusion ginkgo biloba da mo injection combined western medicine treatment in patients with COPD is aggravating period curative effect is distinct,small adverse reactions,and improving the thrombosis in patients with former state parameter indexes and blood rheology change.