丁苯酞治疗急性腔隙性脑梗死患者的临床疗效研究

目的研究丁苯酞治疗急性腔隙性脑梗死(ALI)患者的临床应用效果。方法随机选取我院2013年6月~2016年6月收治的ALI患者76例,分为对照组与观察组。对照组38例,给予阿司匹林肠溶片治疗。观察组38例,给予丁苯酞治疗。比较两组患者临床疗效及治疗前后CSS评分与BI评分。结果观察组治疗有效率(94.74%)明显高于对照组(76.32%),差异具有统计学意义(P0.05)。对照组治疗后CSS评分、BI评分与治疗前比较,差异不具有统计学意义(P0.05)。观察组治疗后CSS评分、BI评分与治疗前比较,差异具有统计学意义(P0.05)。两组治疗前CSS评分、BI评分比较差异不具有统计学意义(P0.05),治疗后观察组CSS评分、BI评分明显优于对照组,差异具有统计学意义(P0.05)。结论丁苯酞可显著提高ALI患者的临床疗效,降低脑卒中风险,改善预后。

Clinical Effect Study of Butylphthalide use for Treatment of Patients with Acute Lacunar Infarction

Objective To study the clinical effect of butylphthalide in the treatment of patients with acute lacunar infarction(ALI).Methods 76 patients with ALI in our hospital in June 2013 ～ 2016 year in June were selected randomly were divided into control group and observation group.The control group of 38 cases,given the treatment of Aspirin Enteric-coated Tablets.38 cases in the observation group were given butylphthalide treatment.The clinical efficacy and CSS score and BI score of two groups were compared before and after treatment.Results The effective rate of the observation group (94.74％) was significantly higher than that of the control group (76.32％),and the difference was statistically significant (P ＜ 0.05).The control group after treatment,CSS score,BI score and treatment before comparison,the difference was not statistically significant (P ＞ 0.05).The observation group after treatment CSS score,BI score and before treatment comparison,the difference has statistical significance (P ＜ 0.05).The two groups before treatment CSS score,BI score was not statistically significant difference (P ＞ 0.05),after treatment,the observation group CSS score,BI score was significantly better than the control group,the difference was statistically significant(P ＜0.05).Conclusion Butylphthalide can significantly improve the clinical efficacy in patients with ALI,reduce the risk of stroke,improve the prognosis.