|
|||||
|
|
| 先天性肾上腺皮质增生症21羟化酶缺陷症合并妊娠的临床及生化特点 | |
| 引用本文： | 卢琳,曾正陪,陆召麟,童安莉,陈适,王永慧,付春莉,陶红,张波. 先天性肾上腺皮质增生症21羟化酶缺陷症合并妊娠的临床及生化特点[J]. 内科急危重症杂志, 2010, 16(1): 13-16 |
| 作者姓名： | 卢琳 曾正陪 陆召麟 童安莉 陈适 王永慧 付春莉 陶红 张波 |
| 作者单位： | 1. 中国医学科学院,北京协和医学院北京协和医院,卫生部内分泌重点室验室,北京,100730 2. 北京安贞医院 3. 中日友好医院 |
| 摘 要： | 目的:分析21OHD女性患者妊娠及其妊娠期间的临床生化特点。方法:对来我院就诊的88例21OHD育龄期女性患者调查其妊娠分娩的情况。结果:在此期间就诊的女性已婚确诊21OHD患者为54名,19名患者共妊娠34次,其中活产婴儿16个,自然流产9次。新生儿男性5例,女性11例。妊娠后血17羟孕酮升高倍数的中位数为8.06倍,6例患者妊娠后改变了糖皮质激素的用法。结论:21OHD患者的妊娠率下降,妊娠期间调整糖皮质激素用法需要个体化。 |
| 关 键 词： | 先天性肾上腺皮质增生 21羟化酶缺陷症 妊娠 |
Clinical and Biochemical Features of Pregnant Women With Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency |
|
| LU Lin,ZENG Zhengpei,LU Zhaolin,et al.. Clinical and Biochemical Features of Pregnant Women With Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency[J]. Journal of Internal Intensive Medicine, 2010, 16(1): 13-16 | |
| Authors: | LU Lin ZENG Zhengpei LU Zhaolin et al. |
| Affiliation: | LU Lin,ZENG Zhengpei,LU Zhaolin,et al.Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Key lab of Ministry of Health,Beijing 100730,China |
| Abstract: | Objective:To investigate the clinical and biochemical features of the pregnant women with the 21-hydroxylase deficiency (21OHD).Methods:The history of pregnancy and delivery were reviewed in 88 female patients with 21 OHD.Results:There were 54 married women were confirmed with 21 OHD.There were 34 pregnancies among 19 female patients,only 16 were normal deliveries with 11 healthy girls and 5 healthy boys.Spontaneous abortion was observed in 9 pregnancies.The median of serum 17 alpha-hydroxyprogesterone was ... |
| Keywords: | Congenital adrenal hyperplasia Deficiency of 21 hydroxylase Pregnancy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |