Antiviral phenolics from Antenoron filiforme var. neofiliforme |
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| Authors: | Shi-Zhong Ma Shu-Hua Luan Xue Zhang Xin-Sheng Yao |
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| Institution: | 1. School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design &2. Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China;3. Shenzhen Salubris Pharmaceuticals Co., Ltd, Shenzhen 518110, China;4. Department of Medicine, Shenyang Chemical Industry School, Shenyang 110122, China |
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| Abstract: | AbstractTwo new phenolics, 1,3-di-O-p-coumaroyl-2′,6′-di-O-acetylsucrose (1) and quercetin 3-O-β-D-apiofuranoyl-(1→2)-α-L-rhamnopyranoside (2), along with nine known compounds (3–11), were isolated from the whole plants of Antenoron filiforme var. neofiliforme. Their chemical structures were characterized on the basis of various spectroscopic techniques. This is the first report of the isolation of phenylpropanoid sucrose (1, 3–4) from the genus Antenoron. The bioassay results showed that compound 11 exhibited antiviral activity against the Coxsackie virus B3 (CVB3). |
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| Keywords: | Polygonaceae Antenoron filiforme var neofiliforme phenolics phenylpropanoid sucrose antiviral activity CVB3 |
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