A new phenanthrenequinone from Dendrobium draconis |
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Authors: | Boonchoo Sritularak Mutita Anuwat |
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Institution: | Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok, 10330, Thailand |
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Abstract: | A number of Dendrobium species (Orchidaceae) have been used as health foods. In Thailand, the tea prepared from the stems of Dendrobium draconis Rchb.f. (Orchidaceae) has been used as a blood tonic. Our phytochemical investigation of this plant led to the isolation of a new compound namely 5-methoxy-7-hydroxy-9,10-dihydro-1,4-phenanthrenequinone (1), along with four known stilbenoids including hircinol (2), gigantol (3), batatasin III (4), and 7-methoxy-9,10-dihydrophenanthrene-2,4,5-triol (5). The structures of these compounds were determined through extensive spectroscopic studies, including 1H and 13C NMR, DEPT, COSY, NOESY, HMQC, HMBC, ESI-MS, and HR-ESI-MS experiments. In the DPPH-free radical assay, these stilbene derivatives showed appreciable antioxidant activity. |
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Keywords: | Dendrobium draconis phenanthrenequinone NMR free radical scavenging |
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