Two new sesquiterpene lactone glycosides from Artemisia frigida Willd. |
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| Authors: | Qing-Hu Wang Yi Sha Wu-Li-Ji Ao Xiu-Lan Wang Xiao-Hua Bao Wen Li |
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| Affiliation: | 1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang, 110016, China;2. College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities , Tongliao, 028000, China;3. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang, 110016, China;4. College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities , Tongliao, 028000, China |
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| Abstract: | The investigation of EtOAc-soluble fraction from the aerial parts of Artemisia frigida has led to the isolation of two new sesquiterpene lactone glycosides, named as artemofriginoside A and artemofriginoside B. Their structures were characterized as 3β-(β-d-glucopyranosyloxy)-8β-(p-hydroxyphenylacetyloxy)-4(15),10(14),11(13)-guaiatrien-1α,5β,6β,7αH-12,6-olide (1) and β-(β-d-glucopyranosyloxy)-8β-(2-hydroxy-3-methylbutanoyloxy)-4(15),10(14),11(13)-guaiatrien-1α,5β,6β,7αH-12,6-olide (2), on the basis of 1D and 2D NMR spectral analysis. |
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| Keywords: | Artemisia frigida sesquiterpene lactone glycoside artemofriginoside A artemofriginoside B |
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