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| Tenascin-C在肾癌中的表达及临床意义 | |
| 引用本文： | 鲁友谊,周荣祥,白岚. Tenascin-C在肾癌中的表达及临床意义[J]. 齐鲁医学杂志, 2010, 25(2): 120-121,124. DOI: 10.3969/j.issn.1008-0341.2010.02.010 |
| 作者姓名： | 鲁友谊 周荣祥 白岚 |
| 作者单位： | 1. 青岛大学医学院附属青岛市立医院泌尿外科,山东,青岛,266011 2. 中国人民解放军第71497部队 |
| 摘 要： | 目的探讨Tenasdn-C（TN—C）在肾癌组织中的表达及临床意义。方法应用免疫组织化学方法检测不同分级的56例肾癌、15例正常肾组织TN—C的表达，分析TN—C与临床病理因素及预后之间的关系。结果肾癌组织TN—C阳性表达率为53．6％（30／56），正常肾组织未检出TN—C阳性表达，两者比较差异有统计学意义（χ^2=7．780，P〈0．01）。TN—C的表达随着癌组织病理学分级、临床分期的增加而增加（P=0．002—0．041）；TN—C阳性表达组与阴性表达组之间的生存率比较差异有统计学意义（χ^2=6．711，P〈0．05）。结论TN-C的表达与肾癌发生、发展及预后有密切的关系。 |
| 关 键 词： | 肾肿瘤 Tenascin-C 免疫组织化学 |
EXPRESSION OF Tenascin-C IN RENAL CARCINOMA AND ITS CLINICAL SIGNIFICANCE |
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| LU YOU-YI,ZHOU RONG-XIANG,BAI LAN. EXPRESSION OF Tenascin-C IN RENAL CARCINOMA AND ITS CLINICAL SIGNIFICANCE[J]. Medical Journal of Qilu, 2010, 25(2): 120-121,124. DOI: 10.3969/j.issn.1008-0341.2010.02.010 | |
| Authors: | LU YOU-YI ZHOU RONG-XIANG BAI LAN |
| Affiliation: | LU YOU-YI,ZHOU RONG-XIANG,BAI LAN(Department of Urology,The Affiliated Qingdao Municipal Hospital of Qingdao University Medical College,Qingdao 266011,China) |
| Abstract: | Objective To investigate the expression of Tenascin-C(TN-C) in renal carcinoma and its clinical significance.Methods The expressions of TN-C in 56 cases of different-grade renal carcinoma and 15 of normal renal tissue were detected immunohistochemically.The correlation of TN-C with clinical pathology and prognosis of the cancer was analyzed. Results The positive rate of TN-C expression in the cancer was 53.6%(30/56),no TN-C was detected in normal renal tissue.The difference of TN-C expression between the tw... |
| Keywords: | Tenascin-C |
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