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sIL—2R检测对喉鳞癌病人临床意义的探讨
摘    要:本文应用双抗体夹心ELISA法和免疫组化法,分别对喉鳞癌病人血清及癌组织内sIL-2R进行了检测。结果表明:喉鳞癌病人血清sIL-2R水平显著增高,且sIL-2R在喉鳞癌晚期癌组织中变化明显。同时探讨其对喉鳞癌病人的临床意义。

关 键 词:喉肿瘤,双抗体夹心ELISA,免疫组织化学,可溶性白细胞介素Ⅱ受体

Detection of sIL-2R in the serum and the tissue of laryngeal squamous cell carcinoma and the clinical significance
Kong Hong,Zhang Xinxin,Li Guangyu,et al. Detection of sIL-2R in the serum and the tissue of laryngeal squamous cell carcinoma and the clinical significance[J]. Journal of Jilin University: Med Ed, 1996, 0(3)
Authors:Kong Hong  Zhang Xinxin  Li Guangyu  et al
Affiliation:Dept.of.E.N.T.The Third Clinical College
Abstract:The paper detected sIL-2R by ELISA and ABC methods. The detection was made inserum of 36 cases with laryngeal carcinoma and 35 normal persons,and in the carcinoma tissue of 25cases,The results showed that serum sIL-2R was much higher in laryngeal carcinoma group thanthat in normal control persons,The pathologic grade and clinical stage were related to sIL-2R level.The sIL-2R in the carcinoma tissue were predominantly high in late laryngeal carcinoma.These re-suIts suggested that detection of sIL-2R had certain instructive significance for patient’s conditionand the prognosis.
Keywords:laryngeal neoplasm  immunohistochemistry  soluble interleukin-2 receptor(sIL-2R):double-antibody-sandwich enzyme-linked immunosorbent assay  
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