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痛风发病机理及其药物治疗现状和展望
引用本文:袁建丽等. 痛风发病机理及其药物治疗现状和展望[J]. 中国药事, 2014, 0(1): 86-90
作者姓名:袁建丽等
作者单位:云南道衍生物科技有限公司,昆明650217
摘    要:目的探讨痛风的中西医发病机理,及其药物治疗情况的研究概况。方法参阅近年来国内外文献资料,并进行整理、综述。结果分别归纳分析了痛风的中医发病机理与人体肝、脾、胃、肾的关系,痛风的西医发病机理与人体尿酸排泄减少和尿酸生成过多的关系。同时,分别总结分析了中、西药物治疗痛风的进展。结论在此基础上,认为结合痛风的中医发病机理,从调节肝、肾、脾、胃功能入手,从中医药和天然药中寻找并开发出疗效明确、毒副反应少的抗痛风和高尿酸血症药物,尤其是治疗慢性痛风的中成药,对痛风药物的发展具有重要意义。

关 键 词:痛风  发病机理  药物治疗  研究  综述

Current Study of Gout Pathogenesis and Medication
Yuan Jianli,Peng Mengxian,Sun Min and Wang Lei. Current Study of Gout Pathogenesis and Medication[J]. Chinese Pharmaceutical Affairs, 2014, 0(1): 86-90
Authors:Yuan Jianli  Peng Mengxian  Sun Min  Wang Lei
Affiliation:(Dao Yan〈 Yun Nan〉 Bio-Tech Co., Ltd., Kunming 650217)
Abstract:Objective To discuss the pathogenesis of gout in Chinese and Western Medicine, and their research profiles of medication. Methods Literatures both in domestic and foreign countries in recent years were reviewed and summarized. Results This article reviewed the current study of gout pathogenesis and medication. Two relationships were summarized and analyzed: one was between traditional Chinese medical pathogenesis and liver, spleen, stomach, kidney, and the other between Western medical pathogenesis and the reduction in uric acid excretion and excessive uric acid production. Meanwhile, the treatment development was summarized and analyzed based on traditional Chinese medicine and Western medicine. Conclusion With traditional Chinese medical pathogenesis of gout concerned, considering regulating the function of liver, kidney, spleen and stomach, medication for gout and hyperuricemia will be developed from traditional Chinese medicine and natural medicine, which is effective and has fewer side effects. This article is important for the development of gout treatment.
Keywords:gout  pathogenic mechanisms  medication  research  overview
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