| 病理性瘢痕中细胞因子的作用 |
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| 引用本文： | 柯丹,刁庆春,李发琪,阎国富. 病理性瘢痕中细胞因子的作用[J]. 国际皮肤性病学杂志, 2007, 33(3): 183-185 |
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| 作者姓名： | 柯丹 刁庆春 李发琪 阎国富 |
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| 作者单位： | 1. 400011,重庆市第一人民医院皮肤科
2. 重庆医科大学生物医学工程系 |
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| 摘 要： | 细胞因子在病理性瘢痕的发病中起着重要的作用，致纤维化细胞因子如转化生长因子-β、结缔组织生长因子、血小板源性生长因子、血管内皮细胞生长因子等促进瘢痕的形成，而另一些细胞因子如干扰素、表皮生长因子、碱性成纤维细胞生长因子等则抑制瘢痕的形成。基因技术与细胞因子结合干预瘢痕的形成，有望成为未来治疗病理性瘢痕的一个新的突破点。
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| 关 键 词： | 瘢痕 细胞因子类 治疗应用 |
| 修稿时间： | 2006-07-31 |
Significance of cytokines in pathologic scar |
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| KE Dan,DIAO Qing-chun,LI Fa-qi,YAN Guo-fu. Significance of cytokines in pathologic scar[J]. International Journal of Dermatology and Venereology, 2007, 33(3): 183-185 |
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| Authors: | KE Dan DIAO Qing-chun LI Fa-qi YAN Guo-fu |
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| Abstract: | Cytokines play an important role in the pathogenesis of pathologic scar. Some fibrosis-inducing cytokines, for example, transforming growth factor-beta, connective tissue growth factor, vascular endothelial growth factor, platelet derived growth factor, etc, promote scar formation, while other cytokines, such as interferon, epidermal growth factor and basic fibroblast growth factor, inhibit the formation of scar. The intervention of scar formation by the combination of gene technique and cytokines is expected to be a breakthrough in the treatment of pathologic scar. |
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| Keywords: | Cicatrix Cytokines Therpeutic uses |
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