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A NOVEL DRB1*0801 HAPLOTYPE CARRYING DRB3*0202 FOUND IN A GERMAN PEDIGREE
Authors:D.-F. CHEN  L. T. PASTUCHA  E. D. ALBERT  I. SEIBERT  A. VOLGGER  Z. YAO  C.-D. PEIN  H. L. TILLMANN  M. P. MANNS  W. STANGEL
Abstract:
DRB1*08 haplotypes have not been known to carry a DRB3 gene. We have found a patient suffering from liver disease who has a novel HLA haplotype of DRB1*0801 with DRB3*0202 as established by family segregation. These two genes were confirmed by sequencing. DR8 and DR52 antigen specificities were serologically detected, indicating expression of these genes.
Keywords:
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