心理干预对全麻手术患者术后血浆皮质醇及儿茶酚胺含量的影响

目的观察心理干预对心脏手术患者围手术期血浆儿茶酚胺及皮质醇的影响。方法100例拟行全麻手术的患者随机分两组：A组为对照组，常规护理；B组为心理干预组，围手术期进行综合心理干预治疗；每组各50例。测定入院时（T1）、手术前（T2）、手术中（T3）、术后4g～72h（T4）分别从外周静脉抽取血标本，测定血浆儿茶酚胺，骨上腺素（E）、去甲肾上腺素（NE）及皮质醇。结果两组患者围手术期血浆皮质醇B组在T2，T3明显低于A组（P〈0.05）；而去甲肾上腺素与肾上腺素水平B组在T2，T3明显低于A组（P〈0.05）结论围手术期实行心理干预，能有效地减轻患者术后的应激反应。

Effect of psychological intervention on stress responses in patient after general anaesthesia

Objective To study the effect of psychological intervention on stress responses in patient after general anaesthesia. Methods one hundred patients scheduled for general surgery were randomly allocated to one of the two groups： A and B. Each group was fifty cases. In group A patients received regular nursing. In group B patients received psychological intervention before operation. Venous blood samples were obtained before psychological intervention （ld before operation） （T1）, Before induction of anesthesia （T2）, during operation （T3）, and 48 - 72 hours after operation （T4） for determination of plasma glucose and cortisoil. Results Plasma levels of E and NE in group B were significantly lower than those in group A at T2 and T3 （P〈0.05） ; and cortisoil were lower in group B than those in group A at T2 and T3 （P〈0.05） too. Conclusions Psychological intervention can effectively relieve stress responses during surgical procedures.