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| 左氧氟沙星治疗耐药性肺结核临床研究 | |
| 引用本文： | 赵维群. 左氧氟沙星治疗耐药性肺结核临床研究[J]. 临床合理用药杂志, 2011, 0(16): 24-25 |
| 作者姓名： | 赵维群 |
| 作者单位： | 四川省宜宾市第一人民医院感染科,644000 |
| 摘 要： | 目的观察左氧氟沙星治疗耐药性肺结核的临床效果。方法 90例耐药性肺结核患者随机分为治疗组和对照组各45例。对照组依药敏试验选择二线治疗药物,治疗组在对照组治疗基础上加用左氧氟沙星。观察2组痰菌和病灶变化情况。结果治疗组痰涂片阴转率高于对照组,浸润病变显著吸收率高于对照组,差异均有统计学意义(P<0.05)。治疗组空洞改善情况优于对照组,差异有统计学意义(P<0.05)。结论左氧氟沙星治疗耐药性肺结核效果满意。 |
| 关 键 词： | 左氧氟沙星 肺结核,耐药性 疗效 |
Clinical study of Levofloxacin in the treatment of drug-resistant tuberculosis |
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| ZHAO Wei-qun. Clinical study of Levofloxacin in the treatment of drug-resistant tuberculosis[J]. Chinese Journal of Clinical Rational Drug Use, 2011, 0(16): 24-25 | |
| Authors: | ZHAO Wei-qun |
| Affiliation: | ZHAO Wei-qun.The First Hospital of Yibin City,Sichuan,Yibin 644000,China |
| Abstract: | Objective To observe the clinical effect of levofloxacin in the treatment of drug-resistant tuberculosis.Methods 90 cases of drug-resistant tuberculosis were randomly divided into treatment group and control group,45 cases of each.The control group received second-line treatment drug according to susceptibility testing,while the treatment group received levofloxacin based on the control group.Sputum and the lesions changes were observed.Results The conversion rate of sputum smear of the treatment group was higher than that of the control group,and the absorption rate of invasive disease was significantly higherthan that of the control group too,the differences were respectively statistically significant （P0.05）.The improvement conditions of the treatment group was better than that of the control group,and the difference was statistically significant （P0.05）.Conclusion Levofloxacin in treatment of resistant tuberculosis is effect. |
| Keywords: | Levofloxacin Drug-resistant tuberculosis Effect |
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