二妙汤加味内服结合外洗治疗湿热浸淫型小儿湿疹72例临床观察

目的]探讨二妙汤加味内服结合外洗治疗湿热浸淫型小儿湿疹的临床疗效.方法]选取2018年6—9月天津市西青区妇幼保健和计划生育服务中心就诊的湿热浸淫型湿疹患儿72例,随机分为治疗组(36例)、对照组(36例).对照组给予丁酸氢化可的松乳膏外涂,治疗组给予二妙汤加味内服加外洗治疗.两组均连续治疗4周,观测4周后临床疗效...

Treatment of 72 cases of infantile eczema with dampness-heat immersion syndrome by internal and external washing with Ermiao Decoction

Objective] To investigate the clinical effect of Ermiao Decoction on treating infantile eczema with dampness-heat immersion syndrome.Methods] From June 2018 to September 2018, the 72 children with damp-heat immersion eczema in Xiqing Maternal and Child Health Care and Family Planning Service Center of Tianjin were selected and randomly divided into treatment group (n=36) and control group (n=36). The control group was externally coated with hydrocortisone butyrate cream, and the treatment group was orally treated with Ermiao Decoction plus external washing. Both groups were treated continuously for 4 weeks, and the clinical efficacy, symptom score changes and pruritus efficacy were observed after 4 weeks, and the recurrence rate was observed for 6 months to understand the long-term efficacy.Results] The total effective rate of EASI (eczema area and severity index score) in the treatment group was 94.44%, which was higher than 88.89% in the control group. After treatment, the skin rash morphology in the treatment group was significantly improved and the area was decreased, and the reduction of skin rash morphology in the treatment group was better than that in the control group, with statistical significance(P<0.05). The effective rate of pruritus in the treatment group was 94.44%, which was significantly higher than that in the control group (77.78%), and the difference was statistically significant (P<0.05). The recurrence rate of the treatment group was 27.78%, significantly lower than that of the control group (78.89%), and the difference was statistically significant(P<0.01).Conclusion] Ermiao Decoction has a significant effect on the treatment of infantile eczema with damp-heat immersion syndrome by oral administration and external washing, which was higher than that of the western medicine group. It not only improved the symptom score and pruritued degree, but also significantly reduced the recurrence rate during follow-up.