淋巴结清扫术对单模式经胸食管切除术治疗食管腺癌的生存率的影响

目的 探讨淋巴结清扫术对单模式经胸食管切除术治疗食管腺癌的生存率的影响.方法 回顾性分析聊城市第三人民医院胸外科2016年1月-2018年1月收治的63例单模式经胸食管切除术治疗的食管腺癌患者临床资料.从性别、年龄、肿瘤部位、T分期、N分期、分化程度、浸润程度、肿瘤直径、淋巴结清扫术式等方面分析影响单模式经胸食管切除术...

Effect of lymph node dissection on the survival rate of single mode transthoracic esophagectomy for esophageal adenocarcinoma

Objective To investigate the effect of lymph node dissection on the survival rate of single-mode transthoracic esophagectomy for esophageal adenocarcinoma. Methods The clinical data of 63 patients with esophageal adenocarcinoma treated by single-mode transthoracic esophagectomy in our hospital from January 2016 to January 2018 were analyzed retrospectively. Gender, age, tumor location, T stage, N stage, degree of differentiation, degree of invasion, tumor diameter and lymph node dissection were analyzed. The recurrence of lymph nodes after two field dissection and three field dissection were compared. Results 63 patients with esophageal adenocarcinoma were treated by single-mode transthoracic esophagectomy. 32 cases survived for 3 years, and the 3-year survival rate was 50.79%. Age, tumor location, T stage, tumor differentiation, invasion, tumor diameter and lymph node dissection were the single factors affecting the prognosis of patients with esophageal adenocarcinoma treated by single-mode transthoracic esophagectomy (P value < 0.05). Age > 60, tumor location in the upper esophagus, T4 stage, low degree of tumor differentiation and two field lymph node dissection were independent risk factors affecting the prognosis of patients with esophageal adenocarcinoma treated by single-mode transthoracic esophagectomy (P value < 0.05). The recurrence rate of lymph nodes in patients with three field dissection was 37.50%, which was lower than 74.36 in patients with two field dissection (P < 0.05). Conclusion Lymph node dissection is an independent factor affecting the survival rate of patients with esophageal adenocarcinoma treated by single-mode transthoracic esophagectomy. Three field dissection may bring survival benefit to patients.