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Contradictory to its effects on thrombin,C1-inhibitor reduces plasmin generation in the presence of thrombomodulin
Authors:Tarandovskiy  Ivan D  Rajabi  Ali A  Karnaukhova  Elena  Buehler  Paul W
Institution:1.Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation Research, Food and Drug Administration, 10903 New Hampshire Avenue, Building 52, Room 4109, Silver Spring, MD, 20993, USA
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Abstract:Journal of Thrombosis and Thrombolysis - C1-inhibitor (C1INH) was shown to enhance thrombin generation (TG) in the presence of thrombomodulin (TM) by reducing production of activated protein C....
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