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| 转化生长因子β和肺纤维化 | |
| 引用本文： | 黄旭晴,梁颇,李万成. 转化生长因子β和肺纤维化[J]. 国际呼吸杂志, 2008, 28(17): 1081-1084 |
| 作者姓名： | 黄旭晴 梁颇 李万成 |
| 作者单位： | 泸州医学院第一附属医院呼吸内科,646000 |
| 摘 要： | 转化生长因子β(transforming growth factor-β,TGF-β)是启动和终止炎症和组织修复的调节因子,是参与调控肺纤维化发生的细胞因子.TGF-β亚单位功能与其种类以及与受体的亲和力有密切关系.TGF-β的信号通路在纤维化的发生发展中起重要作用. |
| 关 键 词： | 肺纤维化 转化生长因子β1 转化生长因子β1 信号通路 |
Transforming growth factor-beta and pulmonary fibrosis |
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| HUANG Xu-qing,LIANG Po,LI Wan-cheng. Transforming growth factor-beta and pulmonary fibrosis[J]. International Journal of Respiration, 2008, 28(17): 1081-1084 | |
| Authors: | HUANG Xu-qing LIANG Po LI Wan-cheng |
| Abstract: | Transforming growth factor-β(TGF-β) is the adjusted factor, involving in progress of pulmonary inflammation, and also involving in chronic tissue reparation. TGF-β is a member of cytokine family involving in pulmonary fibrosis effected by TGF-β. The isoform's activities of TGF-β are closely related to its types and receptors' affinity. The signal pathways of TGF-β are believed to be primarily responsible for pulmonary fibrosis progression. |
| Keywords: | Pulmonary fibrosis Transforming growth factor-β1 Transforming growth factor-β1 Signalpathway |
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