Serial Measurements of Pregnancy-specific β1-glycoprotein (β1SP1) in Patients with Trophoblastic Disease |
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Authors: | F. SEARLE K. D. BAGSHAWE J. DENT B. A. LEAKE |
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Affiliation: | Department of Medical Oncology, Charing Cross Hospital (Fulham), London, England |
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Abstract: | A radioimmunoassay for pregnancy-specific-β1-glycoprotein (Bohn. 1971) has been established with a limit of detection of 2 μMg/litre in serum. The assay has been used to measure serial levels of pregnancy-specific-β1-glycoprotein (β1SP1) in the serum of patients with choriocarcinoma and teratoma for comparison with measurements of the β-subunit of human chorionic gonadotrophin. The value of the assay for β1SP1, in the management of these patients is discussed. |
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