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| 甲磺酸非诺多泮注射液与三种常用输液的配伍稳定性 | |
| 引用本文： | 刘放,周芝芳,孙洁胤,俞建生,章明鹊. 甲磺酸非诺多泮注射液与三种常用输液的配伍稳定性[J]. 浙江省医学科学院学报, 2006, 0(2) |
| 作者姓名： | 刘放 周芝芳 孙洁胤 俞建生 章明鹊 |
| 作者单位： | 浙江省医学科学院药物研究所 浙江震元制药有限公司 |
| 摘 要： | 目的研究室温24小时内甲磺酸非诺多泮注射液与5%葡萄糖注射液、0.9%氯化钠注射液和复方葡萄糖氯化钠注射液的配伍稳定性,为临床用药提供科学依据。方法采用反相高效液相色谱法测定甲磺酸非诺多泮注射液与三种输液配伍后,24小时内非诺多泮的含量及有关物质,同时考察配伍液的外观和pH值。结果在室温条件下,甲磺酸非诺多泮与上述三种输液配伍24小时后,外观、pH值、含量和有关物质均无明显变化。结论甲磺酸非诺多泮注射液可与5%葡萄糖注射液、0.9%氯化钠注射液和复方葡萄糖氯化钠注射液配伍使用。 |
| 关 键 词： | 非诺多泮注射液 输液 配伍稳定性 反相高效液相色谱 |
The Stability of Compatibility of Fenoldopam Mesylate Injection in Three Different Infusions |
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| Liu Fang,Zhou Zhi-fang,Sun Jie-yin,et al. The Stability of Compatibility of Fenoldopam Mesylate Injection in Three Different Infusions[J]. Acta Academiae Medicinae Zhejiang, 2006, 0(2) | |
| Authors: | Liu Fang Zhou Zhi-fang Sun Jie-yin et al |
| Abstract: | Objective To study the stability of compatibility of fenoldopam mesylate injection in three different infusions for 24 hours at room temperature.Methods The content and related substances of fenoldopam mesylate injection in three mixture were determind by HPLC,and then appearance and pH values were deterermined.Results The results showed that there was no significant changes after matching in the appearance,pH values,content and related substances for 24 hours at room temperature.Conclusion Fenoldopam mesylate injection solution could combine with 5% glucose injection,0.9% sodium chloride injection,glucose and sodium choloride injection. |
| Keywords: | Fenoldopam mesylate injection Infusions Compatibility stability RP-HPLC |
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