碳酸锂不良反应回顾性分析

目的 探讨碳酸锂所致药物不良反应的一般规律和特点，为临床合理用药提供参考。方法 采用回顾性研究方法，对1994-2006年2月国内报道的77例碳酸锂不良反应进行分析和综合评价。结果 碳酸锂所致不良反应在18岁。60岁问发生率高，男性患者多于女性患者。不良反应涉及机体多个系统，主要是神经系统损害和过敏反应。大多患者在停药对症治疗后可恢复正常。结论 临床医师、药师应了解碳酸锂所致不良反应的规律和特点，加强其应用的监测，以减少不良反应的发生。

Retrospective study of adverse reactions induced by lithium carbonate

Objective To study the general rules and characteristics of adverse reactions induced by lithium carbonate, in order to provide some references for rational drug uses in the clinic. retrospective analysis, 77 cases with adverse reactions induced by lithium carbonate, reported domestically during 1994 to February 2006, were analyzed and evaluated. Resuits Adverse reactions induced by lithium carbonate mostly occurred in the patients ages between 18-60, male patients were more than female ones. Adverse reactions involved in several system and mainly were damage of the nervous system and anaphylaxis. Most patients were recovered after stopping using lithium carbonate and appropriate treatment. Conclusion Clinical doctors and pharmacists should grasp the rules and the characteristics of adverse reactions induced by lithium carbonate, and strengthen monitoring of its use, in order to reduce occurrence of adverse reactions.