Ⅱ型糖尿病患者的吲哚青绿和荧光素眼底血管造影

目的 观察Ⅱ型糖尿病患者的吲哚青绿血管造影(indocyanine green angiography,ICGA的荧光素眼底血管造影(fundus fluorescein angiography,FFA)的特征,探讨Ⅱ型糖尿病患者脉络膜血管的改变。方法 56例患者采用ICGA和FFA同步造影检查,对两种造影图像进行对比分析。结果 25例(50只眼)直接眼底检查未达到DR分期诊断标准者,其中12例(22只眼)FFA出现异常荧光,占44％,主要表现为点状强荧光．19例(34只眼)ICGA出现异常荧光,占68％,主要表现为中晚期点状强荧光以及早期点状弱荧光;31例(62只眼)直接眼底检查为非增殖期糖尿病视网膜病变者,31例(62只眼)ICGA和FFA均有不同程度异常荧光,在FFA中主要表现为微动脉沼的点状强荧光、出血的遮蔽荧光、毛细血管闭塞的弱荧光,在ICGA中主要表现为晚期斑片状强弱荧光与弥漫性强荧光。结论 ICGA的临床应用发现糖尿病性脉络膜病变的可能,在Ⅱ型糖尿病患者,ICGA是FFA一种有用的补充检查。

Indocyanine green angiography and fundus fluorescein angiography in type 2 diabetes mellitus

Objective Observation on the characteristics of type 2 diabetes mellitus with indocyanine green angiography (ICGA) and fundus fluorescein angiography(FFA),to study changes of choroidal vessels in type 2 diabetes mellitus.Methods The simultanous ICGA and FFA were performed on 56 cases of type 2 diabetes mellitus for comparison and analysis.Results 25 cases(50 eyes) were not found to diabetic retinopathy in direct ophthalmoscopy,12 cases(22 eyes) had the appearance on FFA of abnormal fluorescent(44%),primarily presented spotty hyperfluorescent,19 cases (34 eyes) had the appearance on ICGA of abnormal fluorescent(68%),primarily presented spotty hyperfluorescent in the late phase and hypofluorescent in the early phase.31 cases(62 eyes) were found to nonproliferative diabetic retinopathy in direct ophthalmoscopy,31 cases (62 eyes) had the appearance on ICGA and FFA of abnormal fluorescent.The appearance on ICGA of lobular spotty hyperfluorescent and hypofluorescent in the late phase,with diffuse late-phase hyperfluorescent.Conclusions The possible findings of diabetic choroidopathy with indocyanine green angiography,ICGA maybe a useful adjunct to FFA with type 2 diabetes mellitus.