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Evaluation of the Inflammatory Response to Two Different Intensities of Exercise in Individuals with Heart Failure
Authors:Danielle Aparecida Gomes Pereira  Giane Amorim Ribeiro-Samora  Danielle Soares Rocha Vieira  Leani Souza Máximo Pereira  Fernanda Matos Coelho  Ver?nica Franco Parreira  Maria da Consola??o Vieira Moreira  Maria Clara Noman Alencar  Raquel Rodrigues Britto
Affiliation:(1) Physical Therapy Department, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil;(2) Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil;(3) School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil;(4) University Hospital, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Abstract:The aim of this study is to compare the response of interleukin-6 (IL-6) and soluble tumor necrosis factor alpha receptor 1 (s-TNFr1) to two submaximal intensities of exercise in individuals with heart failure (HF). Thirty-two HF individuals aged 45.53 ± 9.41 years, classes II and III of the New York Heart Association (NYHA) classification underwent two sessions of exercise at low and moderate intensities with blood analysis at baseline, exercise and after exercise. The differences were evaluated by Friedman test and factorial ANOVA. Alpha = 5% was considered. No difference in IL-6 was detected for low intensity. At moderate intensity, there was a significant increase after exercise. The s-TNFr1 increased in moderate-intensity exercise and went back to baseline levels after it. A session of moderate-intensity exercise is better than low-intensity exercise at promoting positive immediate inflammatory responses in individuals with HF class II and III of the NYHA.
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