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内镜下套扎、硬化剂及组织胶栓塞联合治疗食管胃底静脉曲张出血的临床研究
引用本文:赵倩,和水祥,刘亚萍,卢桂芳,任牡丹. 内镜下套扎、硬化剂及组织胶栓塞联合治疗食管胃底静脉曲张出血的临床研究[J]. 临床和实验医学杂志, 2021, 20(3): 279-282
作者姓名:赵倩  和水祥  刘亚萍  卢桂芳  任牡丹
作者单位:西安交通大学第一附属医院消化内科 陕西西安710000;西安交通大学第一附属医院消化内科 陕西西安710000;西安交通大学第一附属医院消化内科 陕西西安710000;西安交通大学第一附属医院消化内科 陕西西安710000;西安交通大学第一附属医院消化内科 陕西西安710000
基金项目:陕西省科技面上项目(编号:2020JM-381)。
摘    要:目的 研究内镜下套扎、硬化剂及组织胶栓塞联合治疗食管胃底静脉曲张出血的临床效果.方法 采用回顾性分析方法 ,研究对象为2018年1月至2019年6月西安交通大学第一附属医院收治的220例食管胃底静脉曲张出血患者.根据不同治疗方式分为对照组(n = 100)和研究组(n = 120).对照组单用内镜下套扎治疗,研究组联用...

关 键 词:食管胃底静脉曲张出血  内镜下套扎  硬化剂  组织胶栓塞

Clinical study of endoscopic ligation,sclerotherapy and tissue glue embolization in the treatment of esophageal and gastric varicose vein bleeding.
Affiliation:(Department of Gastroenterology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'anShaanxi 710000,China.)
Abstract:Objective To study the efficacy of endoscopic ligation,sclerotherapy and tissue glue embolization in the treatment of esophageal and gastric varicose vein bleeding.Methods Retrospective analysis was performed on 220 patients with esophageal and gastric varices bleeding admitted to the First Affiliated Hospital of Xi'an Jiaotong University from January 2018 to June 2019.According to different treatment methods,they were divided into control group(n=100)and study group(n=120).The control group was treated with endoscopic band ligation alone,and the study group was treated with endoscopic band ligation,sclerosing agent and tissue glue embolization.The severity of varicose veins,pain score,esophageal varices diameter,portal vein width,splenic vein width and the success rate of hemostasis,early rebleeding rate and late rebleeding rate after treatment were compared between the two groups before and 3 d after operation.Results There was no significant difference in the severity of varicose veins,pain score,esophageal varices diameter,portal vein width,and splenic vein width before treatment between the two groups(P>0.05);3 d after operation,the two groups had moderate to severe varicose veins rate,pain score,esophageal varicose diameter,Portal vein width and splenic vein width were significantly lower than before treatment(P<0.05);3 d after operation,the study group had moderate to severe varicose vein rate,pain score,esophageal varicose diameter,portal vein width,splenic vein width,early rebleeding rate,and delayed The rebleeding rate was lower than that of the control group,and the success rate of hemostasis was higher than that of the control group(P<0.05).Conclusion The combined application of endoscopic ligation,sclerotherapy and tissue glue embolization in the treatment of esophageal and gastric varicose vein hemorrhage is effective,which can effectively reduce the severity and pain of varicose veins in patients and reduce the rate of rebleeding.
Keywords:Esophageal and gastric varices bleed  Endoscopic ligation  Curing agent  Tissue glue embolization
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