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18F-FDG PET/CT in detection of gynecomastia in patients with hepatocellular carcinoma |
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| Authors: | Hsin-Yi Wang Long-Bin Jeng Ming-Chia Lin Chih-Hao Chao Wan-Yu Lin Chia-Hung Kao |
| Affiliation: | 1. Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan;2. Department of Life Sciences, National Chung Hsing University, Taichung 40227, Taiwan;3. Organ Transplantation Center, China Medical University Hospital, Taichung 40447, Taiwan;4. Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, 40447 Taiwan;5. Department of Nuclear Medicine, E-DA Hospital, I-Shou University, Kaohsiung, 82445 Taiwan;6. Division of Chest Medicine, Department of Internal Medicine, Chang Bing Show Chwan Memorial Hospital, Changhwa 50544, Taiwan;7. Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung 40447, Taiwan |
| Abstract: | ObjectiveWe retrospectively investigate the prevalence of gynecomastia as false-positive 2-[18F]fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging in patients with hepatocellular carcinoma (HCC).MethodsAmong the 127 male HCC patients who underwent 18F-FDG PET/CT scan, the 18FDG uptakes at the bilateral breasts in 9 patients with gynecomastia were recorded as standard uptake value (SUVmax) and the visual interpretation in both early and delayed images.ResultsThe mean early SUVmax was 1.58/1.57 (right/left breast) in nine gynecomastia patients. The three patients with early visual score of 3 had higher early SUVmaxs.ConclusionGynecomastia is a possible cause of false-positive uptake on 18F-FDG PET/CT images. |
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