| 砷的发育毒性的初步研究 |
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| 引用本文： | 马龙,张晨,赛娜娃,阿力木,亚里昆,孜比尼沙.砷的发育毒性的初步研究[J].新疆医科大学学报,1993(2). |
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| 作者姓名： | 马龙 张晨 赛娜娃 阿力木 亚里昆 孜比尼沙 |
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| 作者单位： | 新疆医学院预防医学系卫生毒理学教研组，新疆医学院预防医学系卫生毒理学教研组，新疆医学院预防医学系，新疆医学院预防医学系，预防医学系86级毕业实习生，预防医学系86级毕业实习生 86级毕业实习生，86级毕业实习生 |
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| 摘 要： | 本实验选用NIH种小白鼠,应用Chernoff-Kavlock试验,初步观察了砷的发育毒性。结果显示:(1)染砷各组孕鼠体重、活仔窝率、窝的大小、平均活仔出生体重、出生3整天活仔平均增重和出生3整天平均存活率与溶剂对照组比较均无明显差异;(2)高剂量组(4.5 mg As/kg)仔鼠断乳后体重明显低于溶剂对照组,中低剂量组(0.75 mg As/kg、0.15 mg As/kg)仔鼠体重则明显高于溶剂对照组。结果提示,砷对仔鼠生长发育可能具有双相性影响。
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| 关 键 词： | 砷 发育毒性 小鼠 |
A Preliminary Study on Development Toxicity of Arsenic |
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| Ma Long,et al.A Preliminary Study on Development Toxicity of Arsenic[J].Journal of Xinjiang Medical University,1993(2). |
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| Authors: | Ma Long |
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| Institution: | Ma Long,et al Department of Envirommental Hygiene,Xinjiang Medical College |
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| Abstract: | The development toxicity of arsenic on NIH mice was studied with Chernoff-Kaviock test. The results showed: (1)There was no significant difference between groups of arsenic and the control in Chernoff-Kavlock indexes. (2)In high dose group (4.5 mg As/kg) the body weight of newborn mouse after weaning was lower than that of the control; while body weight of other groups (0.75 mg As/kg, 0.15 mg As/kg) was higher than the control. The results suggested that the arsenic have bipolar effects on development of newborn mouse. |
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| Keywords: | arsenie development toxcity mice |
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