曲美他嗪联合美托洛尔治疗功能性频发室性早搏60例疗效观察

目的:探讨曲美他嗪联合美托洛尔治疗功能性频发室性早搏患者的有效性。方法:选取收治功能性频发室性早搏120例患者,随机分成治疗组和对照组。治疗组使用曲美他嗪片20 mg,3次/d,美托洛尔12.5 mg,2次/d,逐步增加到25 mg,2次/d;对照组使用美托洛尔12.5 mg,2次/d,逐步增加到25 mg,2次/d,治疗2周。结果:治疗组有效率为85%,对照组有效率为70%,两组间比较差异有统计学意义(P<0.05),治疗组患者早搏减少、症状改善程度优于对照组(P<0.05),不良反应无明显差异。结论:曲美他嗪联合美托洛尔治疗频发室性早搏患者临床有效。

Investigate the clinical efficacy of treatment of sixty patients with functional frequent premature ventricular beats by trimetazidine tablets combined with metoprolol tablets

Objective To investigate the clinical efficacy of treatment of functional frequent premature ventricular beats by trimetazidine tablets combined with metoprolol tablets.Method Selecting 120 patients with functional frequent premature ventricular beats who were treated was used as the study object.They were randomly divided into treatment group and control group.The control group was treated with metoprolol tablets （12.5mg twice a day,gradually increase its dosage to 25mg twice a day） .The treatment group was treated with trimetazidine tablets （20 mg three times a day） and metoprolol tablets （12.5 mg twice a day,gradually increase its dosage to 25mg twice a day） .Both groups were treated for two weeks.Results The effective rate was 85% in the treated group and that of the control group was 70%.There was a significant difference between the two groups （P〈0.05） .The reduction of premature ventricular beats and improving clinical symptoms in treat group.It was significant better than the control group （P〈0.05） .Adverse reactions was not significant difference.Conclusion The therapeutic effectiveness of treating functional frequent premature ventricular beats by trimetazidine tablets combined with metoprolol tablets is effective.