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异环磷酰胺联合化疗治疗晚期非小细胞肺癌近期疗效
引用本文:余萍,王更利,李秋. 异环磷酰胺联合化疗治疗晚期非小细胞肺癌近期疗效[J]. 中国医药导刊, 2000, 2(2): 47-48
作者姓名:余萍  王更利  李秋
作者单位:[1]四川省肿瘤医院内科,成都 [2]四川省肿瘤医院药剂科,成都
摘    要:40例晚期非小细胞肺癌患,经用IFO+DDP或IFO+VP-16治疗,2例CR(5%),17例PR(42.5%),CR+PR为47.5%(19/40)。毒性反应主要是骨髓抑制和消化道症状。结果揭示含异环磷酰胺的联合化疗治疗晚期非小细胞肺癌疗效较好,有一定程度骨髓抑制,配合G-CSF治疗恢复较快。

关 键 词:异环磷酰胺 非小细胞肺癌 联合化疗 疗效

The Preliminary Result for the Treatment of Advanced Non - small Cell Lung Cancer with Ifosfamide Containing Regimens
Yu Ping,Wang Geng - li,Li Qiu,Wan Xin. The Preliminary Result for the Treatment of Advanced Non - small Cell Lung Cancer with Ifosfamide Containing Regimens[J]. Chinese Journal of Medicinal Guide, 2000, 2(2): 47-48
Authors:Yu Ping  Wang Geng - li  Li Qiu  Wan Xin
Affiliation:Yu Ping,Wang Geng-li,Li Qiu,Wan Xin(Sichuan Cancer Hospital, Chengdu 61004)
Abstract:40 Cases of advanced non - small cell lung cancer were treated with ifosfamide plus cisplatin regimen versus ifosfamide plus etoposide regimen. The result showed 2 cases CR(5% ), 17cases PR(42. 5% ), CR + PR 47.5% (19/40) . Major toxicity was myelosuppression and gastrointestial reaction. Thus, ifosfamide containing regimens may be selected as effective regimen in advanced NSCLC.
Keywords:ifosfamide  non - small cell lung cancer  combined chemotherapy
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