Trausim种植体植入早期骨结合性能评价

目的:研究Trausim骨内种植体植入早期骨改建过程,检测该骨内种植体的骨结合性能,为其表面处理技术的改进及临床应用提供依据。方法:全麻下拔除14条成年Labrador犬双侧下颌第一前磨牙至第一磨牙(PM1-M1),待拔牙创愈合3个月后,每条犬双侧下颌骨植入6颗骨内种植体,其中一侧为实验组,植入Trausim种植体3颗;对侧为对照组,植入Straumann种植体3颗,非埋入式缝合。实验犬分别于2、4、8、12周处死,取含种植体的骨块,经处理后,行硬组织切片。染色后,行组织学检查,计算骨-种植体结合率(bone-implant contact,BIC%)。采用SPSS 19.0软件包对数据进行统计学处理。结果:84颗种植体在植入时都取得了良好的初期稳定性,愈合良好,无脱落。骨-种植体结合率在8周时达到最高值,Trausim种植体为71.64%±6.66%,Straumann种植体为72.98%±8.97%。第12周稍有降低,达到稳定。2种种植体在不同时期的骨结合率无显著差异(P>0.05)。结论:Trausim种植体在植入早期愈合过程与Straumann种植体骨结合率相似,为其临床应用奠定了坚实基础。

Bone-to-implant contact percentage at Trausim implants:an experimental study in dogs

PURPOSE:The aim of this study was to evaluate the Trausim implants bone remodelling at early stage of implantation,to provide necessary experimental parameters for improving the characteristics of the surface treatment technique.METHODS:14 Labrador dogs were prepared for teeth extraction of the mandible first premolar to first molar under general anesthesia.After bone healing for 3 months,each dog was implanted with 3 Trausim implant and 3 Straumann implant.2,4,8 and 12 weeks later,the animals were sacrificed and bone-to-implant contact(BIC%) was assessed using histological and histomorphometrical methods.All statistical analysis was performed using SPSS 19.0 software package.RESULTS:All 84 implants achieved clinical stability at the time of insertion,the healing was uneventful.Bone-to-implant percentage was highest at 8-week for Trausim implant(71.64%±6.66%) and Straumann implant(72.98%±8.97%).At 12-week it was lower than at 8-week,but stability was as usual.Moreover,at different healing periods,no significant difference for BIC% between Trausim and Straumann implants was found.CONCLUSION:The present study showed that Trausim implants induce good bone-to-implant contact after implantation.The BIC% was similar to Straumann implants.