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白芍总苷合雷公藤多苷治疗类风湿关节炎60例
引用本文:李兴锐,陈茂红,王和融. 白芍总苷合雷公藤多苷治疗类风湿关节炎60例[J]. 安徽中医学院学报, 2011, 30(3): 16-18. DOI: 10.3969/j.issn.1000-2219.2011.03.007
作者姓名:李兴锐  陈茂红  王和融
作者单位:安徽省六安市人民医院风湿免疫科,安徽,六安,237005
摘    要:
目的观察白芍总苷(total glucosides of paeony,TGP)联合雷公藤多苷(Tripteryginum wilfordiipolyglycoside,TWP)治疗类风湿关节炎(rheumatoid arthritis,RA)的临床疗效。方法将120例患者分为2组,治疗组60例采用TGP和TWP治疗,对照组60例采用甲氨蝶呤联合醋氯酚酸治疗,两组疗程均为3个月。结果①治疗组和对照组总有效率分别为90.0%、80.0%,两组总有效率比较,差异无统计学意义(P〉0.05)。②治疗后两组晨僵时间、关节压痛数、关节肿胀数、红细胞沉降率和C反应蛋白水平显著低于治疗前(P〈0.01),但治疗后两组之间比较,上述指标差异无统计学意义(P〉0.05)。③治疗组不良反应发生率显著低于对照组(P〈0.01)。结论 TGP合TWP治疗RA的疗效与甲氨喋呤合醋氯酚酸相当,但TGP与TWP联合方案不良反应较少,患者耐受性强,更适合治疗RA。

关 键 词:类风湿关节炎  白芍总苷  雷公藤多苷

Sixty Cases of Rheumatoid Arthritis Treated with Total Glucosides of Paeony Combined with Tripteryginum Wilfordii Polyglycoside
LI Xing-rui,CHEN Mao-hong,WANG He-rong. Sixty Cases of Rheumatoid Arthritis Treated with Total Glucosides of Paeony Combined with Tripteryginum Wilfordii Polyglycoside[J]. Journal of Anhui Traditional Chinese Medical College, 2011, 30(3): 16-18. DOI: 10.3969/j.issn.1000-2219.2011.03.007
Authors:LI Xing-rui  CHEN Mao-hong  WANG He-rong
Affiliation:LI Xing-rui,CHEN Mao-hong,WANG He-rong(Department of Rheumatology and Immunology,Lu'an People's Hospital,Anhui Lu'an 237005,China)
Abstract:
Objective To observe the therapeutic effects of total glucosides of paeony(TGP) combined with Tripteryginum wilfordii polyglycoside(TWP) in treating rheumatoid arthritis(RA).Methods One hundred and twenty RA patients were divided into two groups.Sixty patients in the treatment group were treated with TGP combined with TWP,and another 60 patients in the control group were treated with Methotrexate(MTX) combined with Aceclofenac.The therapeutic course for two groups was 3 months.Results(1)The total effective ...
Keywords:rheumatoid arthritis  total glucosides of paeony  Tripteryginum wilfordii polyglycoside  
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