糖尿病中医辨证分型与体重指数、胰岛素水平及血脂的相关性研究

目的：研究2型糖尿病中医辨证分型与体重指数、血胰岛素水平及血脂的相关性。方法：选择2型糖尿病患者120例，其中阴虚热盛组、湿热困脾组、气阴两虚组及血瘀络脉组各30例，分别记录体重指数及中医证候积分，并检测空腹胰岛素、餐后2h胰岛素、血脂。结果：各组间高胰岛素血症所占比例的差异有显著性意义（P〈0．01），以湿热困脾型高胰岛素血症所占比例最高；各组血脂异常患者所占比例有显著性差异（P〈0．01），以湿热困脾型血脂异常所占比例最高；四组肥胖患者所占比例有显著性差异（P〈0．01），以湿热困脾型肥胖者所占比例最高。结论：糖尿病患者的体重指数、空腹胰岛素及血脂水平与中医辨证分型存在着一定的相关性，且湿热困脾型患者体重指数、空腹胰岛素及血脂水平与中医其他辨证证型之间存在显著差异，为糖尿病中医辨证分型研究提供了一定的物质研究基础。

Correlation between Differentiation of Symptoms and Signs for Classification of Syndrome of TCM and Body Weight Index,Insulin Level and Blood Lipid

Objective ： To research the correlation between differentiation of symptoms and signs tor classlhcatlon of syndrome of TCM and body mass index, insulin level and blood lipid. Methods： Choose 120 type- I1 dia- betic patients, which were divided into extreme heat with yin asthenia group, heat and humidity distressing spleen group, deficiency of both vital energy and yin group and the blood stasis in collaterals group with 30 pa- tients in each group and the patients were measured TCM Syndrome integral and body mass index, the level of serum levels of insulin and blood - lipid. Results ： The proportion of hyperinsulinemia in the four groups had a significantly different（ P 〈0. 01 ） , in proportion of heat and humidity distressing spleen hyperinsulinemia was the highest. The proportion of dyslipidemia in the four groups was significantly different（ P 〈 0. 01 ）, in pro- portion of heat and humidity distressing spleen dyslipidemia was the highest. The proportion of obese in the four groups had a significant difference（ P 〈0.01 ） , in proportion of heat and humidity distressing spleen obese was the highest. Conclusion： There is a certain correlation between symptoms and signs for classification of syndrome of TCM and BMI, insulin level, blood lipid of the diabetics, and there is a significant difference be- tween the heat and humidity distressing spleen and other differentiation syndrome types in TCM. It provides a certain basis for material research for the study of differentiation of symptoms and signs for classification of syn- drome in TCM.